Author/Editor		Schofield, Paul N.; Gkoutos, Georgios V.; Gruenberger, Michael; Sundberg, John P.; Hancock, John M.
Title		Phenotype ontologies for mouse and man
Type		članek
Vol. and No.		Letnik 3, št. 5/6
Publication year		2010
Volume		str. 281-289
ISSN		1754-8403 - Disease models & mechanisms
Language		eng
Abstract		A major challenge of the post-genomic era is coding phenotype data from humans and model organisms such as the mouse, to permit the meaningful translation of phenotype descriptions between species. This ability is essential if we are to facilitate phenotype-driven gene function discovery and empower comparative pathobiology. Here, we review the current state of the art for phenotype and disease description in mice and humans, and discuss ways in which the semantic gap between coding systems might be bridged to facilitate the discovery and exploitation of new mouse models of human diseases.
Keywords		fenotip kodiranje podatkov delovanje genov phenotype coding data gene function