Author/Editor | Rizvi, Ali A.; Popovic, Djordje S.; Papanas, Nikolaos; Pantea Stoian, Anca; Mahmeed, Wael Al; Sahebkar, Amirhossein; Janež, Andrej; Rizzo, Manfredi | |
Title | Current and emerging drugs for the treatment of atherosclerosis | |
Type | članek | |
Publication year | 2022 | |
Volume | str. str. | |
ISSN | 1477-9072 - Expert review of cardiovascular therapy | |
Language | eng | |
Abstract | Atherosclerosis can be considered a chronic inflammatory process that stands out as a dominant cause of cardiovascular disease (CVD). Since blood lipids are the leading risk factor for atherosclerosis development, lowering low-density lipoprotein cholesterol (LDL-C) and other apolipoprotein B-containing lipoproteins reduces the risk of future cardiovascular events. However, there has been significant progress in developing lipid-lowering drugs for aggressive management of dyslipidemia, the rates of CVD events remain unacceptably high, so there is great need to identify novel therapeutic pathways targeting the atherosclerosis process. | |
Keywords | atherosclerosis lipoproteins developing drugs ateroskleroza lipoproteini razvoj zdravil |