Author/Editor     Rizvi, Ali A.; Popovic, Djordje S.; Papanas, Nikolaos; Pantea Stoian, Anca; Mahmeed, Wael Al; Sahebkar, Amirhossein; Janež, Andrej; Rizzo, Manfredi
Title     Current and emerging drugs for the treatment of atherosclerosis
Type     članek
Publication year     2022
Volume     str. str.
ISSN     1477-9072 - Expert review of cardiovascular therapy
Language     eng
Abstract     Atherosclerosis can be considered a chronic inflammatory process that stands out as a dominant cause of cardiovascular disease (CVD). Since blood lipids are the leading risk factor for atherosclerosis development, lowering low-density lipoprotein cholesterol (LDL-C) and other apolipoprotein B-containing lipoproteins reduces the risk of future cardiovascular events. However, there has been significant progress in developing lipid-lowering drugs for aggressive management of dyslipidemia, the rates of CVD events remain unacceptably high, so there is great need to identify novel therapeutic pathways targeting the atherosclerosis process.
Keywords     atherosclerosis
lipoproteins
developing drugs
ateroskleroza
lipoproteini
razvoj zdravil