Author/Editor		Zupančič, Daša; Veranič, Peter
Title		Nanodiamonds as possible tools for improved management of bladder cancer and bacterial cystitis
Type		članek
Vol. and No.		Letnik 23, št. 15
Publication year		2022
Volume		str. 1-17
ISSN		1422-0067 - International journal of molecular sciences
Language		eng
Abstract		Nanodiamonds (NDs) are a class of carbon nanomaterials with sizes ranging from a few nm to micrometres. Due to their excellent physical, chemical and optical properties, they have recently attracted much attention in biomedicine. In addition, their exceptional biocompatibility and the possibility of precise surface functionalisation offer promising opportunities for biological applications such as cell labelling and imaging, as well as targeted drug delivery. However, using NDs for selective targeting of desired biomolecules within a complex biological system remains challenging. Urinary bladder cancer and bacterial cystitis are major diseases of the bladder with high incidence and poor treatment options. In this review, we present: (i) the synthesis, properties and functionalisation of NDs; (ii) recent advances in the study of various NDs used for better treatment of bladder cancer and (iii) bacterial cystitis; and (iv) the use of NDs in theranostics of these diseases.
Keywords		rak mehurja bakterijski cistitis nanodiamanti bladder cancer bacterial cystitis nanodiamonds