Author/Editor		Hrastar-Kostešić, V; Hren-Vencelj, H
Title		Laboratorijska dijagnostika klamidijskih uretritisa
Type		članek
Source		In: Petričević I, editor. Dijagnostički postupci u kliničkoj obradi infektoloških bolesnika. Radovi 1. hrvatski stručno-znanstveni sastanak infektologa, mikrobiologa i epidemologa; 1992 svi 21-22; Pula. Zagreb: Hrvatski liječnički zbor,
Publication year		1993
Volume		str. 127-30
Language		cro
Abstract		Culture in cycloheximide-treated McCoy cells, direct immunofluorescence (IF) test (ORION DIAGNOSTICA) and indirect microimmunofluorescence (MIF) (OWN ANTIGEN) test were compared for the detection of Chlamydia trachomatis in urethral specimens from 162 men with nongonococcal urethritis (NGU). We tested all asymptomatic men for control group. Chlamydial antigen were detected with IF test in sediment of the first void urine. A total of 43 infections were diagnosed, for a prevalence of 26.5 pct. We found chlamydial antigen in sediment of six patients of control group, for a prevalence of 26.5 pct. The sensitivity and specificity of direct IF were 87.5 pct and 97.5 pct. when compared with the culture technique. The sensitivity and specificity of indirect IF for IgA antibodies were 40 pct. and 87.3 pct, and for IgG antibodies were 44 pct. and 95.8 pct. Direct test had good characteristics and can be used in routine diagnostic of chlamydial urogenital infections. Sensitivity of serological test was low and can not use only this test for laboratory diagnosis of local infections.
Descriptors		URETHRITIS CHLAMYDIA INFECTIONS CROATIA FLUORESCENT ANTIBODY TECHNIQUE CELLS, CULTURED