Author/Editor		Jakić-Razumović, J; Labar, B; Coer, A; Radman, I
Title		Regija nukleolarnog organizatora u malignih ne-Hodgkinovih limfoma
Translated title		Nucleolar organizer region in malignant non-Hodgkin's lymphomas
Type		članek
Source		Liječ Vjesn
Vol. and No.		Letnik 114
Publication year		1992
Volume		str. 18-21
Language		cro
Abstract		Nucleolar organizer region-associated proteins (AgNORs) have been studied in parafin sections of 15 non-Hodgkin's lymphomas by a silver staining technique. On the basis of Working Formulation of malignant non-Hodgkin's lymphomas all studied cases were divided into three groups. A statistically significant difference was found between number of AgNORs in the nuclei of low-grade lymphomas (mean 2.654 per nucleus), and also between intermediate-grade (mean 1.588 per nucleus)and high-grade malignant lymphomas. Significant difference was also observed between AgNOR area in high-grade and low-grade malignant lymphomas and between high-grade and intermediate-grade malignant lymphomas. However no statistically significant differences between all three studied groups with regard to the size of nucleus were found. It is suggested that this method can be very useful in the diagnosis of malignant non-Hodgkin's lymphomas.
Descriptors		LYMPHOMA, NON-HODGKIN'S NUCLEOLUS ORGANIZER REGION LYMPHOMA, HIGH-GRADE LYMPHOMA, INTERMEDIATE-GRADE LYMPHOMA, LOW-GRADE