Author/Editor		Marin, J
Title		The role of Herpes simplex virus and human papillomaviruses in triggering malignancy
Type		članek
Source		Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.		Letnik 4, št. 3
Publication year		1995
Volume		str. 95-8
Language		eng
Abstract		Certain DNA viruses are important as known causes of cancers in humans. Oncogenesis by DNA viruses is best understood for polyoma-, papilloma- and adenoviruses. All of them contain genes that behave as oncogenes. As for herpesviruses there is suggestion that a cellular oncogene might be involved. A number of HSV-specific proteins are produced and expressed by the transformed cells. Herpes simplex virus type 2 was seriously implicated in the etiology of cancer of the cervix. During the past years the theory of herpes simplex virus oncogenesis has lost favour in the face of mounting evidence to incriminate human papillomaviruses in the same disease.
Descriptors		SIMPLEXVIRUS PAPILLOMAVIRUS, HUMAN CELL TRANSFORMATION, NEOPLASTIC NEOPLASMS