Author/Editor		Potočnik, M; Hren-Vencelj, H
Title		Evaluation of roxithromycin in the treatment of urogenital chlamydial infections
Type		članek
Source		Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.		Letnik 4, št. 3
Publication year		1995
Volume		str. 127-9
Language		eng
Abstract		Background. Chlamydia trachomatis infections represent the most frequent sexually transmitted disease in developed countries and probably also worldwide. In women inflammation may spread to involve the internal reproductive organs, which may lead to extrauterine pregnancy and tubal infertility. Methods. Twenty patients (15 men and five women) with proven chlamydial infection of the lower urogenital tract were treated with the macrolide antibiotic roxithromycin in a single daily dose of 300 mg for 10 days. Before the treatment, the causative organism was detected with a direct immunofluorescent method in swab specimens collected from the urethra and-or cervical canal. The test was repeated after the treatment. Results. Microbiological cure was achieved in 19 patients (95 pct.), and clinical symptoms disappeared in all 20 patients studied (100 pct.).
Descriptors		CHLAMYDIA INFECTIONS CHLAMYDIA TRACHOMATIS UROGENITAL DISEASES ROXITHROMYCIN