Author/Editor     Srčič, S; Planinšek, O; Sollner, M; Pečar, S
Title     Termične lastnosti N-(7-oksoacil)-L-alanil-D-izoglutaminov
Translated title     Thermal behaviour of N-(7-oxoacyl)-L-alanyl-D-isoglutamines
Type     članek
Source     Farm Vestn
Vol. and No.     Letnik 47, št. 1
Publication year     1996
Volume     str. 55-62
Language     slo
Abstract     Dezmuramyidipeptides N-(7-oxoacyl)-L-alanyl-D-isoglutamines are substances with similar effects on imune system as natural imunomodulator N-ace-tylmuramyldipeptide. In investigated molecules lipophilicity was changed by incorporation of methylene groups in acyl part. Influence of such structural change of N-(7-oxoacyl)-L-alanyl-D-isoglutamines on their melting point and melting enthalpy was studied. Decrease of melting point and melting enthalpy with increased lenght of alkyl chain was found. metastable polymorphic structures and thermal instability of some analogues were also discovered.
Descriptors     ACETYLMURAMYL-ALANYL-ISOGLUTAMINE
HEAT
TEMPERATURE