Author/Editor | Muzlovič, I | |
Title | Zdravljenje bolnišnične pljučnice | |
Translated title | Treatment of hospital-acquired pneumonia | |
Type | članek | |
Source | Med Razgl | |
Vol. and No. | Letnik 34, št. 4 | |
Publication year | 1995 | |
Volume | str. 523-30 | |
Language | slo | |
Abstract | Hospital-acquired pneumonia accounts for significant morbidity and mortality in hospitalized patients. Gram-negative bacilli and Staphylococcus aureus are the most common isolates in these patients. Since the ethiology of the disease is usually unknown, empirical broad-spectrum antibiotic therapy is given based on the severity of illness, time of onset, specific risk factors and local prevalence of pathogens. Treatment with a single broad-spectrum antibiotic agent (third-generation of cephalosporins, carbapenemes and fluoroquinolons) is recommended in the absence of specific risk factors and Pseudomonas aeruginosa. Combination treatment modalities with beta-lactam antibiotics and aminoglycosides is still the cornerstone of empirical antibiotic treatment of severe hospital-acquired pneumonia. | |
Descriptors | PNEUMONIA HOSPITALS ANTIBIOTICS CROSS INFECTION RISK FACTORS HOSPITALS |