| Author/Editor | Karrer, K; Micksche, M; Pridun, N; Theuer, W; Ulsperger, E; Orel, J; Eržen, J; Hrabar, B; Klevišar, M; Debevec, M; Rott, T | |
| Title | Surgery in SCLC as first step of multimodality treatment | |
| Type | članek | |
| Source | Anticancer Res | |
| Vol. and No. | Letnik 14 | |
| Publication year | 1994 | |
| Volume | str. 327-31 | |
| Language | eng | |
| Abstract | 186 patients received surgery for cure followed by agressive randomized chemotherapy and PCI. After a median follow-up time of about 60 months the observed 4-year overall survival rate for patients completely resected was: 58% for 68 patients with pT1-3NoMo, and 33% for 27 patients with pT1-3 pN2Mo stages of SCLC. These promising results have to be confirmed by larger cooperative studies to support the recommendation to initiate surgery without delay, i.e. without preoperative chemotherapy for SCLC as well as for the non-SCLCs. From 148 patients in ISC study III after preoperative (neoadjuvant) schemotherapy only 12 received surgery for pT1-3N2Mo but only one of them survived 36 months and none 48 months p.o. | |
| Descriptors | LUNG NEOPLASMS CARCINOMA, SMALL CELL SURVIVAL RATE NEOPLASM STAGING FOLLOW-UP STUDIES MULTICENTER STUDIES CYCLOPHOSPHAMIDE DOXORUBICIN LOMUSTINE VINCRISTINE METHOTREXATE IFOSFAMIDE MESNA |