Author/Editor		Sepčić, J; Morović, M; Poljak, I; Ružić-Sabljić, E; Materljan, E; Šepić-Grahovac, D; Milohanić, S
Title		Prevalence of Borrelia burgdorferi antibodies in a high-risk zone for multiple sclerosis (Gorski Kotar, Croatia)
Type		članek
Source		Neurol Croat
Vol. and No.		Letnik 43, št. 4
Publication year		1994
Volume		str. 241-6
Language		eng
Abstract		An analysis was made of the prevalenc eof B.burgdorferi antibodies in subjects from o high risk zone for multiple sclerosis, Gorski Kotar, Croatia, using an indirect immunofluorescence assay. A total of 61 clinically definite multiple sclerosis patients and 84 controls participated in the study. The participants were divided into two groups. The first group consisted of patients and controls who were native-born residents of Gorski Kotar, while the second group consisted of native-born non-residents of the area studied. The difference in the prevalence of B. burgdorferi antibodies in the groups examined was not significant. These results indicate that B.burgdorferi is not a signifivant factor in the etiopathogenesis of multiple sclerosis in a high risk zone. Our preliminary study of B.burgdorferi antibody prevalence among the domestic and wild animals of the region, supported this view.
Descriptors		MULTIPLE SCLEROSIS ANTIBODIES, BACTERIAL BORRELIA BURGDORFERI CROATIA CASE-CONTROL STUDIES FLUOROIMMUNOASSAY