Author/Editor     Urleb, U; Krbavčič, A; Sollner, M; Kikelj, D; Pečar, S
Title     Synthesis of phthalimido-desmuramylpeptide analogues as potential immunomodulating agents
Type     članek
Source     Arch Pharm (Weinheim)
Vol. and No.     Letnik 328, št. 2
Publication year     1995
Volume     str. 113-7
Language     eng
Abstract     The preparation of immunologically active phthalimido desmuramylpeptide analogues 2e-h, 4c-d, and 7b is described. The N-acetylmuramic acid in the muramyl dipeptide has been replaced by a phthaloylated acyclic moiety such as N-phthaloylated amino acids 1a-c, 2-(2-phthalimidoethoxy)acetic acid 3, or by the carbocyclic rac. trans-2-(2'-phthalimidocyclohexyloxy)acetic acid 6.
Descriptors     ADJUVANTS, IMMUNOLOGIC
PEPTIDES
PHTHALIMIDES
ADJUVANTS, IMMUNOLOGIC
CYCLOPHOSPHAMIDE
IMMUNOSUPPRESSIVE AGENTS
MICE
PEPTIDES
PHTHALIMIDES