Author/Editor | Urleb, U; Krbavčič, A; Sollner, M; Kikelj, D; Pečar, S | |
Title | Synthesis of phthalimido-desmuramylpeptide analogues as potential immunomodulating agents | |
Type | članek | |
Source | Arch Pharm (Weinheim) | |
Vol. and No. | Letnik 328, št. 2 | |
Publication year | 1995 | |
Volume | str. 113-7 | |
Language | eng | |
Abstract | The preparation of immunologically active phthalimido desmuramylpeptide analogues 2e-h, 4c-d, and 7b is described. The N-acetylmuramic acid in the muramyl dipeptide has been replaced by a phthaloylated acyclic moiety such as N-phthaloylated amino acids 1a-c, 2-(2-phthalimidoethoxy)acetic acid 3, or by the carbocyclic rac. trans-2-(2'-phthalimidocyclohexyloxy)acetic acid 6. | |
Descriptors | ADJUVANTS, IMMUNOLOGIC PEPTIDES PHTHALIMIDES ADJUVANTS, IMMUNOLOGIC CYCLOPHOSPHAMIDE IMMUNOSUPPRESSIVE AGENTS MICE PEPTIDES PHTHALIMIDES |