Author/Editor		Žargi, M; Šmid, L; Fajdiga, I; Bubnič, B; Lenarčič, J; Oblak, P
Title		Detection and localization of early laryngeal cancer with laser induced fluorescence - preliminary report
Type		članek
Source		In: Miklavčič D, Bajd T, Stanič U, editors. Proceedings of the 9th international conference on mechanics in medicine and biology; 1996 Jun 30-Jul 4; Ljubljana. Ljubljana: Slovenian society of medical and biological engineering,
Publication year		1996
Volume		str. 606-8
Language		eng
Abstract		Fluorescence detection using differences in autofluorescence between normal and malignant tissues offers new possibilities of detecting and localizing early laryngeal carcinoma. Fluorescence imaging was performed using a specially designed devide that exploits differences of fluorescent properties of normal and cancerous tissues without photodynamic drugs. The fluorescence was induced by helium-cadmium laser, captured by an image intensified camera and displayed on video monitor after previous computerization. 30 patients (in 18 of them malignancy was suspected) were taken in evaluation. Laryngoscopic appearance obtained by standard laryngomicroscopy was compared to fluorescence image, to computerized fluorescence intensity measurement and to histological findings. The experience from this study shows that autofluorescence larygoscopy could be a useful complementary method in detecting laryngeal malignancies.
Descriptors		LARYNGEAL NEOPLASMS FLUORESCENT DYES LASERS LARYNGOSCOPY