Author/Editor		Kozak, Matija
Title		Kronična venska insuficienca in limfedem
Translated title		Chronic venous insufficiency and lymphedema
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 35, št. Suppl 2
Publication year		1996
Volume		str. 153-9
Language		slo
Abstract		The pathophysiological characteristics of microcirculation and the immediate surrounding tissues in chronic venous insufficiency are described in the paper. In spite of extensive knowledge of morphological changes in this disease, the mutual connections between various factors influencing it are still unclear. Several hypotheses which attempt to explain the formation of these changes and the course of the disease in chronic venous insufficiency are described in this review. Most hypotheses claim that in addition to increased pressure, the influence of the immune system, which triggers a positive feedback loop in chronic venous insufficiency and probably contributes significantly to lymphedema, is also important.
Summary		V članku so opisane patofiziomorfološke značilnosti mikrocirkulacije in neposrednega okolnega tkiva pri kronični venski insuficienci in limfedemu. Ob sicer obsežnem znanju o morfoloških spremembah pa je medsebojna povezava različnih vplivov še nedorečena. V članku navajamo več hipotez, ki poskušajo razložiti nastanek sprememb in potek bolezni pri kronični venski insuficienci. Večina avtorjev meni, da je ob povečanem tlaku pomemben tudi vpliv imunskega sistema, ki sproži pozitivno povratno zanko pri kronični venski insuficienci in verjetno pomembno sodeluje tudi pri limfedemu.
Descriptors		VENOUS INSUFFICIENCY LYMPHEDEMA MICROCIRCULATION