Author/Editor		Profant, Milan; Galbavy, Štefan; Šebova, Irina; Korch, Jan
Title		Classification of laryngeal cancer precursors: development and state-of-the-art
Translated title		Razvrstitev prekanceroz raka na grlu: razvoj in doktrina danes
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 35, št. Suppl 6
Publication year		1996
Volume		str. 113-20
Language		eng
Abstract		In the retrospective study authors have analyzed histological findings on 108 patients with laryngeal cancer precursors. Histological findings have been reclassified according to Friedmann-Ferlito classification. The development of particular stages of precanceroses have been evaluated. The tendency towards malignant transformation has been seen in stages IV and V of laryngeal precanceroses (carcinoma in situ, microinvasive carcinoma). no malignization occured in the group of stage I (epithelial hyperplasia). The diagnosis of laryngeal cancer precursors can be given exclusively according to the histological investigation. Surgical treatment of laryngeal cancer precursors is recommended.
Summary		V pregledni študiji avtorji analizirajo histološke izvide 108 bolnikov s prekancerozami raka na grlu. Histološke ugotovitve so razvrstili po Friedmann-Ferlitovi razvrstitvi. Ocenili so razvoj posameznih stadijev prekanceroz. Težnjo k maligni izroditvi so ugotovili pri četrtem in petem stadiju prekanceroz (karcinom in situ, mikroinvazivni karcinom). Do rakave izroditve ni prišlo v skupini s prvim stadijem prekanceroze (epitelijska hiperplazija). Diagnozo prekanceroze raka na grlu lahko postavimo edinole na osnovi histološkega pregleda. Priporočljivo je kirurško zdravljenje.
Descriptors		LARYNGEAL NEOPLASMS NEOPLASM STAGING PRECANCEROUS CONDITIONS HYPERPLASIA AGE FACTORS