Author/Editor		Aničin, Aleksandar; Šmid, Lojze
Title		Verukozni karcinom v področju glave in vratu
Translated title		Verrucous carcinoma of the head and neck
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 35, št. Suppl 6
Publication year		1996
Volume		str. 229-33
Language		slo
Abstract		Verruocous carcinoma is a rare, highly differentiated variant of squamous carcinoma. Setting a proper diagnosis demands persistency of the clinical and pathologist and their mutual collaboration. In the years 1979-1994, at the Department of Otolaryngoloty and Cervicofacial Surgery, University Medical Centre, Ljubljana, Slovenia, we treated 22 patients with verucous carcinoma. The larynx was affected most frequantly (17 patients), particularly the region of the glottis (15 patients). Treatment was surgical in the majority of cases (19 patients). Three patients refused laryngectomy and were treated with irradiation. The median follow-up was 5 years (range 2-16 zears). With surgery we experienced no recurrences in our series. Radiotherapy was insuccessful in two cases. Among all patients with surgically treated laryngeal tumours, partial procedures were performed in ten cases (72 %). Surgery remains the mainstay of head and neck verrucous carcinoma therapy.
Summary		Verukozni karcinom je redka, dobro diferencirana inačica ploščatoceličnega karcinoma. Za postavitev pravilne diagnoze je potrebna vztrajnost klinika in platologa ter nujno medsebojno sodelovanje. V letih 1979-1994 smo na Kliniki za otorinolaringologijo in cervikofacialno kirurgijo v Ljubljani zdravili 22 bolnikov z verukoznim karcinomom. Najpogosteje je bilo prizadeto grlo (17 bolnikov), predvsem področje glotisa (15 bolnikov). Bolnike smo največkrat zdravili kirurško (19 bolnikov). Trije so odklonili laringektomijo in bili zdravljeni z obsevanjem. Bolnike smo spremljali od 2 do 16 let (mediana 5 let). Pri nobenem izmed kirurško zdravljenih bolnikov ni pričlo do ponovitve bolezni. Pri dveh obsevah bolnikih je bilo zdravljenje neuspešno. Pri desetih od vseh na grlu operiranih bolnikov (72 %) smo naredili ohranitveni kirurški poseg. Kirurško zdravljenje ostaja metoda izbora pri zdravljenju verukoznega karcinoma področja glave in vratu.
Descriptors		HEAD AND NECK NEOPLASMS CARCINOMA, VERRUCOUS