Author/Editor		Bajrović, Fajko; Sketelj, Janez
Title		Collateral sprouting of cutaneous sensory afferents
Translated title		Kolateralno brstenje senzoričnih živcev v koži
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 65, št. 10
Publication year		1996
Volume		str. 543-7
Language		eng
Abstract		Background. Peripheral nerve injury is usually folloowed by regeneration of the injured nerve fibers and/or by collateral sprouuuuting of the adjacent uninjured nerve(s). If the injured axonds filed to reinnervate the denervated area, collateral sprouting might be the only possibility for functional recovery. Collateral sprouting is essentially a branching outgrowth of additional terminals from uninjured axons in response to partial denervation of the target tissue, leading to expansion of the innervation field of uninjured neurons into foreign territory. It bas been observed in sensory, motor, and autonomic nerves. Conclusions. Different types of sensory axons differ in their ability to extend sprouts into the adjacent denervated skin. Nociceptive A delta fibers display the greatest potential to sprout. Collateral sprouts originate either from the nodes of Ranvier or from the axon terminal.
Descriptors		PERIPHERAL NERVES NERVE REGENERATION AXONS SKIN NERVE GROWTH FACTORS