Author/Editor		Gubina, M; Botta, GA; Logar-Car, G; Ferlan-Marolt, V; Avšič-Županc, T; Ihan, A
Title		Helicobacter pylori gastritis in children long-term follow-up after eradication
Translated title		Helicobacter pylori gastritis pri otrocih - dolgotrajno spremljanje eradikacije
Type		članek
Source		Alpe Adria Microbiol J
Vol. and No.		Letnik 5, št. 1
Publication year		1996
Volume		str. 23-8
Language		eng
Abstract		Rationale. Purpose of the study was to establish the relationship of subjective symptoms to gastroscopy findings and immune response in children with regard to the duration of gastric-infection symptoms after helicobacter pylori eradication and to follow up the course of recovery. Methods. In this prospective study, the clinical and immune responses of 30 children, divided into a short-term medical history group (A) and a long-term medical history group (B), were evaluated. Eradication of H. pylori was diagnosed histologically at the first post-treatment check-up. Long-term follow-up laid emphasis on subjective symptoms and anti-H. pyloriIgG titres in sera. Results. After four weeks' treatment, eradication was reached in 83% of cases. Group A had worse clinical symptoms and higher titres than patients in group B. Long-term follow-up demonstrated successful eradication in 63% of children. In group A, the children had more vigorous clinical symptoms and eradication was exapressed less frequently and persisted for a shorter length of time than for patients in group B. Conclusions. Quantitative IgG determination using the Hel-p Test proved u useful method for monitoring treatment of H. pylori infection in children.
Descriptors		HELICOBACTER INFECTIONS IMMUNOGLOBULINS, GAMMA-CHAIN CHILD FOLLOW-UP STUDIES TIME FACTORS IMMUNOENZYME TECHNIQUES TREATMENT OUTCOME