Author/Editor     Bole-Vunduk, B
Title     Vpliv felodipina, primerjan z verapamilom in diltiazemom, na arterijski krvni tlak in frekvenco srčnega utripa pri anesteziranih podganah in podganah z uničenim osrednjim živčnim sistemom
Translated title     Influence of felodipine in comparison with verapamil and diltiazem on the arterial pressure and heart rate in normotensive and pithed rats
Type     članek
Source     Farm Vestn
Vol. and No.     Letnik 47, št. 4
Publication year     1996
Volume     str. 417-24
Language     slo
Abstract     The effect of calcium antagonist felodipine on arterial blood pressure and heart rate were studied in normotensive and pithed rats and compared with that of verapamil and diltiazem. Intravenous administration of felodipine, diltiazem and verapamil induced decrease of arterial pressure in anesthetized normotensive rats. The hypotensive action of felodipine was greater and lasted longer in comparison with that of verapamil and diltiazem, and it was accompanied by moderate increase in heart rate. In pithed rats intravenous administration of felodipine, but not verapamil and diltiazem, produced periferal vasodilatation and hence reduction in arterial pressure.
Descriptors     FELODIPINE
VERAPAMIL
DILTIAZEM
BLOOD PRESSURE
HEART RATE
RATS