Author/Editor		Trevisan, G; Cattonar, P; Nobile, C; Perkan, V; Stinco, G
Title		Dermatological manifestations of lyme borreliosis
Type		članek
Source		Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.		Letnik 5, št. 3-4
Publication year		1996
Volume		str. 101-7
Language		eng
Abstract		Lyme Borreliosis is a multisystemic infection involving skin, joints, the nervous system, the heart and eyes. As of yet four different genospecies of Borrelia burgdorferi have been identified: Borrelia burgdorferi sensu stricto, Borrelia garinii, Borrelia afzelii, and Borrelia japonica. Different strains of borreliae have been associated with different clinical manifestations of Lyme Borreliosis. Lyme Borreliosis is classically descriibed as having three clinical stages or, similar to syphilis, an early phase and a late one. The early infection corresponds to the first stage, the late infection includes the second and the third stages. Skin manifestations of Lyme Borreliosis could be classified into five categories. The first one is characterized by skin manifestations proven to be caused by Borrelia burgdorferi infection, including erythema migrans, lymphadenosis benigna cutis and acrodermatitis chronica atrophicans. The second category covers controversial Lyme Borreliosis manifestations, such as lichen sclerosus et atropjicus, morphea, scleroderma, Scleredema of Buschke, atrophoderma of Pasini and Pierini, Parry-Romberg syndrome (facial hemiatrophy) and Shulman's fasciitis. The third category encompasses granuloma annulare, atypical persistent pityriasis rosea and pityriasis lichenoides which are skin lesions occasionally related to Lyme Borreliosis. Urticaria, erythema nodusum and papular acrodermatitis (Giannotti Crosti syndrome) have been classifiied as reactive Lyme Borreliosis skin manifestations. The last category of diseases includes exceptional skin manifestations duriing Lyme Borreliosis such as nodular panniculitis (Weber-Christian), B-cell cutaneous lymphoma and juvenile chronic myeloid leukemia.
Descriptors		LYME DISEASE SKIN MANIFESTATIONS ERYTHEMA CHRONICUM MIGRANS ACRODERMATITIS LICHEN SCLEROSUS ET ATROPHICUS SCLERODERMA, CIRCUMSCRIBED SCLERODERMA, SYSTEMIC FACIAL HEMIATROPHY GRANULOMA ANNULARE