| Author/Editor | Bregant, L; Tomšič, M | |
| Title | Neonatalni lupusni sindrom | |
| Translated title | Neonatal lupus syndrome | |
| Type | članek | |
| Source | Slov Pediatr | |
| Vol. and No. | Letnik 2, št. 4 | |
| Publication year | 1995 | |
| Volume | str. 44-6 | |
| Language | slo | |
| Abstract | We report on a case of y newborn baby girl with a cutaneous form of neonatal lupus syndrome, representing a model of a passively acquired autoimmunity. Maternal autoantibodies against the Ro/SS-A and La/SS-B antigens are transmitted throuogh the placenta and may cause eutaneous, heart or liver defects, or blood anomalies. Treatment of cutaneous lesions consists of locally applied corticosteroids; while for heart lesions, mainly manifested as irreversible complete heart block, the insertion of a pacemaker is the only solution. The newborn baby girl had an isolated cutaneous lesion, which slowly and spontaneously regressed. A positive correlation in the levels of autoantibodies between the mother and the newborn was found. | |
| Descriptors | LUPUS ERYTHEMATOSUS, CUTANEOUS INFANT, NEWBORN |