Author/Editor		Beović, Bojana
Title		Glivične okužbe pri nevtropeničnih bolnikih
Translated title		Fungal infections in neutropenic patients
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 35, št. Suppl 7
Publication year		1996
Volume		str. 49-61
Language		slo
Abstract		Fungal infections usually develop in the later stages of neutropenia. The most important risk factors are the duration of neutropenia and the neutrophil cell count. Candida and Aspergillus are known to be the most common pathogens. Other fungi are increasingly recognized as pathogens in neutropenic patients. Clinical manifestations of fungal infections in neutropenics depend upon the organ involved, the fungal species seems less important. The course of the disease is acute or chronic. The diagnosis of fungal infections in severely ill netropenic patients can be difficult. Isolation of fungi from sterile sites or histology are required for definitive diagnosis. Treatment of fungal infections in neutropenic patients in a broader sense include prophylaxis, empirical treatment, specific therapy and secondary prophylaxis. Amphotericin B remains the agent of choice for the treatment of most fungal infections in neutropenic hosts. Newer agents such as lipid tormulations of amphotericin B and triazoles seem to be successful in some circumstances.
Descriptors		NEUTROPENIA MYCOSES RISK FACTORS