Author/Editor		Ličina, Milan; Vitorović, Sveto; Švigelj, Viktor; Gostič-Kumar, Marta
Title		Wilsonova bolezen in duševne motnje: prikaz dveh primerov
Translated title		Wilson's disease and mental disturbances: two cases
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 66, št. 2
Publication year		1997
Volume		str. 57-9
Language		slo
Abstract		Background. More than 80 years of investigation and management of patients with Wilson's disease, which is due to copper accumulation in various organs, has shown that there is frequently an unacceptable delay in establishig the correct diagnosis. Usually the diagnosis is made when signs and symptoms of the copper intoxication is fully developed and different organ systems are involved and full or partial restoration of organ function is difficult to achieve. In certain percentage mental disorders are the leading symptoms. Methods. The purpose of our article is to present two patients with Wilson's disease in whom ubiquitious mental disorders were the leading signs and symptoms. Conclusions. Diagnosis of the Wilson's disease is easy to make, when it is considered, the therapy is successful and for life. Two patients with Wilson's disease were described in whom the leading and variable signs and symptoms of the psychiatric disorders were fully developed, what is usually a characteristic in psychiatric diseases of an organic origin. The diagnosis of the Wilson's disease was made with the delay and treatment was not successful.
Summary		Izhodišča. Več kot 80 let je minilo, odkar je bila prvič opisana Wilsonova bolezen, do katere pride zaradi kopičenja bakra v telesu. Kljub mnogim raziskavam in kliničnim ugotovitvam pogosto pozno pomislimo na to bolezen, po navadi šele, ko je klinična slika že razvita, okvare organov zaradi kopičenja bakra pa pogosto nepopravljive. Bolezen se lahko primarno kaže na različnih organskih sistemih, a lahko začne tudi kot duševna motenost. Metode. Namen prispevka je prikaz dveh bolnikov z Wilsonovo boleznijo, pri katerih so bili prisotni in vodilni simptomi in znaki duševne motenosti. Zaključki. Diagnoza Wilsonove bolezni ni težavna, če le pomislimo nanjo, zdravljenje pa je do konca življenja. V našem prispevku smo prikazali dva bolnika, pri katerih so bili vodilni znaki in simptomi psihične motenosti, ki so se spreminjali, kar je značilno za spremembe, ki jih najdemo pri organsko pogojenih psihiatričnih boleznih. Diagnoza Wilsonove bolezni je bila postavljena pozno, zdravljenje pa ni bilo učinkovito.
Descriptors		HEPATOLENTICULAR DEGENERATION ADULT