Author/Editor		Vrecl, M; Jan, J; Pogačnik, A; Bavdek, SV
Title		Transfer of planar and non-planar chlorobiphenyls, 4,4'-DDE and hexachlorobenzene from blood to milk and to suckling infants
Type		članek
Source		Chemosphere
Vol. and No.		Letnik 33, št. 11
Publication year		1996
Volume		str. 2341-6
Language		eng
Abstract		The transfer coefficients of tetra- and hexachlorobiphenyls (PCB-54; -80; -155; and -169), HCB and 4,4'-DDE between milk and blood were monitored for eight weeks in sheep previously administered with these compounds by intramuscular injection. Analyses were performed by high resolution gas chromatography. The milk/blood ratio on a fat basis was close to 1 for HCB, over 1 for 4,4'-DDE, PCB-155, and -169 and below 1 for PCB-54 and -80. It is speculated that the deviation from the ratio 1 results from the interactions of organochlorines with (lipo)proteins in blood and/or milk. In milk, the enrichment of 4,4'-DDE, PCB-155 and -169 was observed. The relative toxicity expressed by the toxic equivalent (on a fat basis) was approximately 2.5 times higher in milk than in blood.
Descriptors		DDE HEXACHLOROBENZENE MILK POLYCHLORINATED BIPHENYLS ANIMALS, SUCKLING CHROMATOGRAPHY, HIGH PRESSURE LIQUID DDE HEXACHLOROBENZENE INJECTIONS, INTRAMUSCULAR LACTATION MILK PESTICIDE RESIDUES POLYCHLORINATED BIPHENYLS SHEEP