Author/Editor     Stojan, Jure
Title     Fitting the kinetic equation for slow-binding ligand by microcomputer
Type     članek
Source     Vestn Slov Kem Druš
Vol. and No.     Letnik 34, št. 2
Publication year     1987
Volume     str. 233-41
Language     eng
Abstract     A computer program in BASIC for fitting kinetic data to rate equation is presented. As a model function, the intagrated kinetic equation for a slow reversible binding of a ligand to macromolecule was chosen. The Gauss-Newton interative non-linear-regression method was used to calculate the corresponding non-linear parameters and Gaussian elimination as a method for solving n simultaneus linear equations in n unknowns. By changing the model function in the program other kinetic equations with non-linear parameters can be fitted successfully.
Descriptors     LIGANDS
KINETICS
MICROCOMPUTERS
ENZYMES