Author/Editor		Funa, Andreja; Šavs, Tina; Škrgat, Sabina
Title		Kako dolgo imajo bolniki z erythema migrans prisesane klope
Translated title		Tick attachment times in patients with erythema migrans
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 35, št. 3
Publication year		1996
Volume		str. 297-307
Language		slo
Abstract		Experiments on animals have demonstrated that during the initial 24 hours of tic attachment, the likelihood of transmission of Borrelia burgdorferi, the causative agent of Lyme disease, from an infected tick to the host is negligible. The risk of infection increases abruptly with attachment times 48 hours or longer. The aim of the study was to determine whether this observation applies to humans. In our prospective study, patients with Erythema migrans-like skin lesions were examined in the Lyme borreliosis Out-patient Clinic of the Department of Infectious Diseases and Febrile Illnesses in July and August 1994. From 220 patients with typical erythema migrans lesions, we selected 100 patients who recalled the longest possible time of tick attachment. They were divided into two groups according to the length of tick attachment. Twenty-two per cent of patients reportedly removed the tick within the first 12 hours of attachment, and 66 per cent within the first 24 hours. The results of the study showed that removing an infected tick from the skin within the first 48 hours of attachment does not prevent the transmission of Borrelia burgdorferi to the host.
Summary		V poskusih na živalih so ugotovili, da je možnost za okužbo z Borrelio burgdorferi, povzročiteljem Lymske borelioze, v prvih 24 urah prisesanosti okuženega klopa zanemarljiva in da se začne strmo povečevati šele, kadar je klop prisesan 48 ur in več. Preveriti smo želeli, ali to velja tudi pri ljudeh. Raziskava je prospektivna. Pregledali smo bolnike, ki so bili julija in avgusta 1994 napoteni v Ambulanto za Lymsko boreliozo na Kliniki za infekcijske bolezni in vročinska stanja v Ljubljani zaradi kožnih sprememb sumljivih za erythema migrans, in v raziskavo vključili 220 bolnikov s tipičnim erythema migrans. Na osnovi njihovih anamnestičnih podatkov smo izdvojili 100 takih, ki so lahko dovolj zanesijivo ocenili najdaljši možni čas prisesanosti klopa. Bolnike smo razdelili v razrede glede na najdaljši možni čas prisesanosti klopa. Rezultati naše naloge kažejo, da odstranitev klopa v prvih 48 urah po vbodu ne zagotavlja, da s tem preprečimo Lymsko boreliozo, saj je 22% naših bolnikov ocenilo, da so klopa, ki jih je okužil z B. burgdorferi, odstranili že v prvih 12 urah prisesanosti, 66% pa v prvih 24 urah.
Descriptors		ERYTHEMA CHRONICUM MIGRANS LYME DISEASE ADOLESCENCE ADULT MIDDLE AGE AGED TICKS BITES AND STINGS