Author/Editor		Lešničar, Gorazd
Title		Dva sporadična primera legionarske bolezni v Celju
Translated title		Two sporadic cases of legionnaries' disease in Celje
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 66, št. 3
Publication year		1997
Volume		str. 133-6
Language		slo
Abstract		Backgraund. With the first outbreak of an epidemic Legionnaires' disease in Slovenia we met five years ago that is in 1991 at the general hospital in Jesenice. Afterwards this apportunistic infection showed up rarely, mostly sporadicaly, in health institutions as well as in community-acquirement. Epidemiologic circumstances remained often unexplained. A hope in a faster and more frequent detection of this disease arises with the progress in microbiologic diagnostics: the proof of early antigens of the causative agent in cultures and identification of legionella DNA. Methods. At the general Hospital in Celje two sporadics of Legionnaires' disease are described whitch call attention of presence of legionella infection with us too. We found out that the infection might be also fulminant if the patient was young and supposed to be previously healthy. Conclusions. Into the differential diagnosis of atypic pneumonias and fabrile disease Legionnaires' disease should be included expecially in patients who do not react to doctrinary empiric antibiotic treatment, first of all because of a timely therapy with an affective antibioti, that is erythromycin in high doses.
Summary		Izhodišča. Z epidemijo legionarske bolezni smo se v Sloveniji srečali prvič pred petimi leti, 1. 1991, v bolnišnici na Jesenicah. Nato se je ta oportunistična okužba pojavljala le redko, večinoma sporadično, tako v zdravstvenih ustanovah kot v domačem okolju. Epidemiološke okoliščine so ostale pogosto nepojasnjene. Upanje v hitrejše in pogostejše odkrivanje te bolezni vzbuja napredek v mikrobiološki diagnostiki: dokazovanja zgodnjih antigenov povzročitelja v kužnini in ugotavljanje legionelne DNK. Metode. Opisali smo prva sporadična primera legionarske bolezni v celjski bolnišnici, ki opozarjata na navzočnost legionel tudi pri nas. Videli smo, da okužba lahko poteka fulminantno, tudi če gre za mlajšo, poprej domnevno zdravo osebo. Zaključki. V diferencialno diagnostiko atipičnih pljučnic in vročinskih bolezni moramo zlasti pri bolnikih, ki ne reagirajo na doktrinarno empirično antibiotično zdravljenje, vselej vključiti tudi legionarsko bolezen, predvsem zaradi pravočasne terapije z učinkovitim antibiotikom, tj. eritromicinom v visokih odmerkih.
Descriptors		LEGIONNAIRES' DISEASE MIDDLE AGE ADULT