Author/Editor | Jezeršek, Pavle; Accetto, Rok; Kveder, Tanja | |
Title | Efekt kaptoprila na transport natrijevih ionov preko membran eritrocitov: poročilo o delu za leto 1987 | |
Type | monografija | |
Place | Ljubljana | |
Publisher | Univerzitetni klinični center, Bolnišnica dr. Petra Držaja | |
Publication year | 1987 | |
Volume | str. 23 | |
Language | slo | |
Abstract | Captopril lowers blood pressure even in patients with low plasma renin activity; mechanisms other than renin inhibition may be important for the action of Captopril. We investigate the effect of Captopril on 22Na+ efflux in vitro in red blood cells from healthy males. We concluded that Captopril blocks ouabain-sensitive 22Na+ efflux and the effect of Captopril has physiologic correlates - potassium induced relaxation of smooth muscles in rat aorta is depressed. | |
Descriptors | CAPTOPRIL ERYTHROCYTE MEMBRANE NA(+)-K(+)-EXCHANGING ATPASE |