Author/Editor     Jezeršek, Pavle; Accetto, Rok; Kveder, Tanja
Title     Efekt kaptoprila na transport natrijevih ionov preko membran eritrocitov: poročilo o delu za leto 1987
Type     monografija
Place     Ljubljana
Publisher     Univerzitetni klinični center, Bolnišnica dr. Petra Držaja
Publication year     1987
Volume     str. 23
Language     slo
Abstract     Captopril lowers blood pressure even in patients with low plasma renin activity; mechanisms other than renin inhibition may be important for the action of Captopril. We investigate the effect of Captopril on 22Na+ efflux in vitro in red blood cells from healthy males. We concluded that Captopril blocks ouabain-sensitive 22Na+ efflux and the effect of Captopril has physiologic correlates - potassium induced relaxation of smooth muscles in rat aorta is depressed.
Descriptors     CAPTOPRIL
ERYTHROCYTE MEMBRANE
NA(+)-K(+)-EXCHANGING ATPASE