Author/Editor		Kajba-Veninšek, Simona; Kajba, Stanislav; Koren, Igor
Title		Uporaba pršilnikov in vzorec zdravil pri odraslih bolnikih z astmo in bolnikih s KOPB v celjski regiji od 1994-95
Translated title		Device compliance and pattern of drugs taken by adult asthmatics and COPD patients in Celje region during 1994-95
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 66, št. 5
Publication year		1997
Volume		str. 239-43
Language		slo
Abstract		Background. The major advantage of delivering drugs directy into the airways via inhalation is that high concentrations can be delivered more effectively to the airways, and systemic side effects are avoided or minimized. The most common drugs taken by adult asthmatics of COPD patients and the correct inhalers' usage were assessed in the survey. Methods. Questionnaires were send by mail to the random sample of 300 patients with COPD or asthma in Celje region in September 1994. There was nearly the same percent of COPD patients and asthmatics in the sample. The correct inhalation technique was then checked by ten general practitioners previously instructed by pulmologist. Results. Of the 300 subjects in the study sample, 219 (73%) returned the questionnaire 6 (2%) were incompletely filled in and were excluded. The remaining 213 (71%) questionnaires (123 asthmatics and 90 COPD patients) were included in the study material. Inhaled short-acting-beta2-agonist (78%) and inhaled corticosteroids (51%) were the most common drugs used in asthmatics. Sustained-release theophylline (66.7%) was the most common used drug in COPD patients. On the other band asthmatics used inhalers, with or without spacer, correctly in higher percent than COPD patients (73.2% vs 46.7%, p = 0.0017). Conclusions. These findings suggest that COPD patients have lower complicance to inhaled therapy than asthmatics. Low device complicance in COPD patients may be one of the reason why theophyllines are still so extended drugs in these patients.
Summary		Izhodišča. Glavna prednost vnosa zdravil v dihala z inhalacijo je vnos večjih koncentracij zdravil z manjšimi sistemskimi stranskimi učinki. V študiji smo ugotavljali najpogosteje uporabljena zdravila pri odraslih bolnikih z astmo in bolnikih s KOPB ter preverjali pravilno uporabo pršilnikov. Metode. V septembru 1994 smo naključno izbranemu vzorcu 300 bolnikov s KOPB ali astmo v celjski regiji na dom poslali vprašalnike. Izbrali smo približno enak delež bolnikov z astmo in bolnikov s KOPB. 10 splošnih zdravnikov je preverjalo pravilno tehniko uporabe pršilnika. Rezultati. Od 300 anketiranih bolnikov je vrnilo vprašalnike 219 bolnikov (73%). 6(2%) vprašalnikov je bilo nepopolno izpolnjenih, zato smo jih izključili iz raziskave. V raziskavo smo vključili preostalih 213 (71%) vprašalnikov, od tega je bilo 123 bolnikov z astmo in 90 bolnikov s KOPB. Bolniki z astmo so najpogosteje uporabljali inhalacijske kratko delujoče beta2-agoniste (78%) ter inhalacijske kortikosteroide (51%). Največ uporabljeno zdravilo pri bolnikih z astmo so bili dolgo delujoči teofilinski preparati (66,7%). Bolniki z astmo so v primerjavi z bolniki s KOPB v večjem odstotku pravilno uporabljali pršilnike z ali brez nastavka (73,2% proti 46,7%, p =0.0017). Zaključki. Ugotovili smo, da bolniki s KOPB v večji meri nepravilno uporabljajo pršilnike kot bolniki z astmo. To je lahko eden od razlogov za še vedno veliko razširjenost teofilinskih preparatov med bolniki s KOPB.
Descriptors		LUNG DISEASES, OBSTRUCTIVE ASTHMA ADMINISTRATION, INHALATION SLOVENIA RETROSPECTIVE STUDIES ADOLESCENCE ADULT MIDDLE AGE AGED