Author/Editor		Noč, M; Weil, MH; Štajer, D
Title		Myocardial dysfunction after cardiac resuscitation
Type		članek
Source		In: Roussos C, Armaganidis A, Papadatos J, et al, editors. Free papers 2 of the 8th European congress of intensive care medicine; 1995 Oct 18-22; Athens. Bologna: Monduzzi editore S.p.A.,
Publication year		1995
Volume		str. 667-70
Language		eng
Abstract		We investigated post-resuscitation cardiac function in a portine model of cardiac arrest. Ventricular firillation (VF) was induced in 11 domestic pigs. After 4 min of untreated VF, precordial compression and mechanical ventilation were initiated and maintained for 8 min. Electrical defibrillation restored spontaneous circulation in 6 of 11 animals which were observed for a period of 180 min. Decreases in stroke volume index from prearrest value of 1.13 ml/kg to 0.74 ml/kg (p<0.05) were associated with transient increases in heart rate from 145 to 198 bpm (p<0.05). Cardiac index, which was comparable with prearrest levels immediately after successful resuscitation, decreased significantly at 30 minutes and remained depressed. Pulmonary artery occlusive pressure, mean aortic pressure, right atrial and mean pulmonary artery pressure remained essentially unchanged. Accordingly, our studies indicate an impairment in cardiac function after successful cardiac resuscitation.
Descriptors		HEART ARREST CARDIOPULMONARY RESUSCITATION VENTRICULAR FIBRILLATION HEART FUNCTION TESTS RESPIRATION, ARTIFICIAL SWINE HEART RATE STROKE VOLUME