Author/Editor		Dubois, B
Title		The cognitive syndrome of progressive supranuclear palsy
Translated title		Kognitivni sindrom pri progresivni supranuklearni paralizi
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 65, št. Suppl 3
Publication year		1996
Volume		str. III-69-71
Language		eng
Abstract		The article favours the existence of a specific pattern of cognitive impairment in progressive supranuclear palsy (PSP) consisting of cognitive slowing, impairment of executive functions and forgetfulness. The slowing of central processing in PSP patients is postulated to be due to striatofrontal dysfunction. PSP patients are also impaired in lexical and design fluency, motor series, sorting task, problem solving and abstract thinking, suggesting a dysexecutive sydrome. Memory function dependent on the integrity of the temporal lobes seem to be relatively preserved, but memory functions supposed to depend on the integrity of the frontal lobe are impaired in PSP.
Summary		Prispevek podpira domnevo, da je progresivni supranuklearni paralizi (PSP) pridružena specifična kognitivna motnja, ki sestoji iz kognitivne upočasnitve, motenih eksekutivnih funkcij in pozabljivosti. Upočasnitve centralnega procesiranja pri PSP pripisuje striatofrontalni disfunkciji. Bolniki s PSP dosegajo slabše rezultate pri testih leksične in oblikovne zmožnosti, razvrščanja motoričnih serij, reševanja problemov in obstraktnega mišljenja, kar vse so značilnosti diseksekutivnega sindroma. Spominske funkcije, vezane na temporalni reženj, so relativno očuvane, tiste, odvisne od frontalnega režnja, pa motene.
Descriptors		SUPRANUCLEAR PALSY, PROGRESSIVE COGNITION DISORDERS