Author/Editor		Skaza-Maligoj, Alenka; Hren-Vencelj, Helena; Storman, Alenka; Eržen, I
Title		Prevalence of chlamydial urethritis in males in the Celje region
Translated title		Razširjenost uretritisov pri moških v celjski regiji, ki jih povzroča Clamydia trachomatis
Type		članek
Source		Alpe Adria Microbiol J
Vol. and No.		Letnik 5, št. 4
Publication year		1996
Volume		str. 243-51
Language		eng
Abstract		Rationale. This study focused on the prevalence of Chlamydia trachomatis urethritis in the Celje region. The research project included 44 males with symptoms of urethritis and 218 healthy males. Our objectives were to identify the prevalence of chlamydial urethritis in sexually active men and to evaluate the diagnostic tests. Methods. Urethral swabs and morning-catch urine specimens were taken from all subjects. C. trachomatis antigens were detected by direct immunofluorescence (DIF) in urethral swabs and by enzyme immunoassay (EIA), nucleic acid hybridization and the DIF tests in urine sediments. Chlamydial antigens were detected in the control group by DIF, EIA and nucleic acids hybridization in urine sediments. Results. In the study group, the chlamydial aetiology of urethritis, detected by DIF in urethral swabs, was evidenced in 11.4% of cases. The result was 15.9% (7/44) when all three tests for C. tranchomatis in both urethral swabs and urine were combined. The proportion of control group patients with chlamydial antigens detected in urine was 2.8%. This figure rose to 3.2% (7/218) when nucleic acid hybridization and EIA were combined. Conclusions. The study confirmed the diagnostic value of urine specimens for the detection of C. tranchomatis antigens by EIA and nucleic acid hybridization test.
Descriptors		URETHRITIS CHLAMYDIA TRACHOMATIS ADULT FLUORESCENT ANTIBODY TECHNIQUE, DIRECT IMMUNOENZYME TECHNIQUES NUCLEIC ACID HYBRIDIZATION