Author/Editor		Moser, Ewald; Gomišček, Gregor; Schuster, Johann; Holzmueller, Peter
Title		Spin-spin relaxation time manifestations of tissue degradation
Type		članek
Source		Croat Chem Acta
Vol. and No.		Letnik 65, št. 1
Publication year		1992
Volume		str. 211-4
Language		eng
Abstract		The changes of spin-spin (T2) reacation time in rat liver and muscle biopsies after tissue excision were investigated by low resolution NMR spectrometry. Relaxation times T2 were determined during the first four hors after the tissue excision at 9-minute time intervals, keeping the tissue at constant temperature. Series of measurements were performed at three different temperatures (7, 20, 37 degrees C). Changes in pH were measured under the same experimental conditions. Due to degradation processes after tissue excision, molecular and structural changes take place in the cells and are manifested in variations of T2 value. An empirical relation is suggested to describe the observed correlation between T2 and pH, as well as temperature in the excised liver and muscle tissue.
Descriptors		MUSCLE, SKELETAL LIVER NUCLEAR MAGNETIC RESONANCE HYDROGEN-ION CONCENTRATION TEMPERATURE RATS, SPRAGUE-DAWLEY