Author/Editor     Bačer-Kermavner, L; Veble, A; Valentinčič, B; Virant-Klun, I; Mivšek, J; Meden-Vrtovec, H; Tomaževič, T
Title     Pregnancy rates following embryo transfer on 4th vs 2nd day after retrieval of oocytes, fertilized by intracytoplasmic sperm injection
Type     članek
Source     In: Gomel V, Leung PCK, editors. In vitro fertilization and assisted reproduction. Proceedings of the 10th world congress of in vitro fertilization and assisted reproduction; 1997 May 24-28; Vancouver. Bologna: Monduzzi Editore,
Publication year     1997
Volume     str. 901-4
Language     eng
Abstract     To avoid multiple pregnancies resulting from IVF, and the associated complications we started transferring 2 embryos at the morula developmental stage on the 4th day after retrieval, i.e. on the 6th day after hCG. Having achieved the same pregnancy rates as with the transfer of 3 embryos on the 2nd day after oocyte retrieval, we decided to apply the same procedure with embryos achieved by intracytoplasmic sperm injection (ICSI). In the first group of patients embryo transfer (ET) was performed on day 4 and in the second group on day 2 after oocyte retrieval. Both groups of patients were comparable by age, number of previous cycles, indication for IVF and type of ovarian stimulation. The highest pregnancy rate was achieved with the transfer of 2 embryos on the 4th day (38.5%), whereas the transfer of 2 embryos on the 2nd day resulted in the 25% pregnancy rate. Although nearly one half of embryos did not reach the morula stage, the pregnancy rate was higher after ET on day 4. We may presume that ET on the 4th day after oocyte retrieval improves synchronization between the embryonic stage of development and endometrial receptivity.
Descriptors     EMBRYO TRANSFER
OOCYTES
FERTILIZATION IN VITRO
PREGNANCY