Author/Editor		Vidmar, Stanko
Title		Vpliv prognostičnih dejavnikov pri reseciranem, nemikrocelularnem karcinomu pljuč, stadijev I, II in IIIa, na nadaljnji potek bolezni in preživetje
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1996
Volume		str. 119
Language		slo
Abstract		Since the second decade of the twentieth century, the incidence of carcinoma of the lung has risen alarmingly in all economically developed and developing countries of the world. It now stands as one of the most common causes of death from cancer and is, in fact, the most common cause of death in all men with cancer. We are not satisfied with the results of treatment of lung cancer. The overall five year survival rate of the entire patient group is about 10o/o. Only one third of the patients with lung cancer can be identified as operative candidates. For the others an operation is not indicated, because they have advanced disease. The current treatment results for non-sinall cell lung cancer clearly calls for improved therapy and also for a careful selection of patients for the treatinent options from which they are most likely to benefit. A detailed knowledge of prognostic factors is important for achieving these goals. The introduction and refinement of TNM staging of bronchogenic carcinoma were significant advancements in the understanding and treatment of this disease. Today, for patients with non-small-cell lung carcinoma, the stage of disease at diagnosis and treatment is the most important prognostic factor. However, within a staging group there is no means of determining which patients are at risk of local recurrence or distant metastases after therapy. The significant variability of survival within staging groups requires further prognostic factors, independent of stage, that will determine which patients are at risk for recurrence. In the prospective study on 279 consecutive patients, radically resected stage I, II and IIIa non-small cell lung cancer, I have tried to find the significant prognostic factors. I have investigated the following prognostic factors: gender, age, time from discovery to operation, nutritional status, weight loss, performance status, clinical symptoms before operation, smoking habits, WBC, (Abstract truncated at 2000 characters).
Descriptors		LUNG NEOPLASMS CARCINOMA, NON-SMALL-CELL LUNG PROGNOSIS ADULT MIDDLE AGE NEOPLASM STAGING AGE FACTORS SURVIVAL ANALYSIS TREATMENT OUTCOME PROSPECTIVE STUDIES POSTOPERATIVE COMPLICATIONS SMOKING PNEUMONECTOMY