Author/Editor     Sedonja, Irena
Title     Prispevek enofotonske emisijske tomografije pri pregledu bolnikov s sumom na kostne metastaze
Type     monografija
Place     Ljubljana
Publisher     Medicinska fakulteta
Publication year     1997
Volume     str. 78
Language     slo
Abstract     Aim: The purpose of this study was to find out if SPET can show more metastases in spine than planar scintigraphy and consequently the indications for SPET in conjuction with planar scintigraphy. We also wanted to see if SPET is more accurate at differentiating between malignant and benign lesions. Methods: Thirtyseven patients without knoown malignancy (11 male, 26 female, average age 58,7 years) and 38 patients with confirmed malignancy (27 male, 11 female, average age 65,5 years, malignancies: lung 13, prostatic 5, gastric 3, colonic 3, renal 3, plasmocytoma 3, lymphoma 2, breast 2, bladder 2, bile ducts 1, laryngeal 1) were included in the study. Planar and SPET scintigraphy was performed on the same day, 2 to 3 hours after injection of 500-600 MGq 99m/TC-DPD. Benign and malignant lesions were abalysed about number, location, type and intensity on planar and SPET scintigraphy. Lesions proved to be malignant or benign by radiological methods. Results: Number of lesions: 75,6% more lesions in 31,7% more vertebras were demonstrated on SPET with respect to planar scintigraphy. The difference in detection of degenerative disk diseases (SPET 39,1%, planar sc. 32,2%) and osteoporotic compression fractures (SPET 27/32, planar sc. 22/32) on SPET and planar images was not significant. SPET was considerable better in detection of degenerative joint diseases (SPET 24,3%, planar sc. 6,3%, p<0,01), interspinous pseudoarthroses (SPET 8/13, planar sc. 1/13, p<0,01) and metastases (SPET 58/64 (90,6%), planar sc. 42/64 (65,6%), p<0,01). Intensity of lesions: The lesions shown on SPET were more conspicuous than the same lesions shown on planar scintigrams. In degenerative diseases the average intensity on SPET was 2,02+-0,53, on planar scan 1,63+-0,62, p<0,01. When metastases were considered, the average intensity on SPET scan was 2,20+-0,61, and planar scan 1,86+-0,83, p<0,05. (Abstract truncated at 2000 characters).
Descriptors     SPINAL NEOPLASMS
TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON
BONE NEOPLASMS
TECHNETIUM TC 99M MEDRONATE
SPINAL DISEASES
SPINAL STENOSIS
SPINAL OSTEOPHYTOSIS
TUBERCULOSIS, SPINAL
SPINAL FRACTURES