Author/Editor		Takač, Iztok; Arko, Darja; Gorišek, Borut
Title		Osnovne značilnosti raka jajčnikov
Translated title		The basic characteristics of ovarian cancer
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 36, št. 1
Publication year		1997
Volume		str. 57-71
Language		slo
Abstract		The ethiology of ovarian cancer is unknown. Some women, however, seem to be at great risk for the development of this serious disease, which is the major killer among gynaecologic malignancies. The tumor most frequently arises from the superficial ovarian epithelium. A variety of histologic types of ovarian cancer can be identified: serous, mucinous, endometrioid, clear-cell, mixed, undifferentiated, unclassified and Brenner ovarian tumours. As to the degree of differentation, we distinguish between well differentiated, moderately and poorly differentiated carcinomas. Borderline malignant tumours with specific histologic and biologic features form a separate group. Less frequently, malignant tumours occur as a result of metastatic spread directly to the abdominal cavity via lymphatic channels into the retroperitoneal space, and hemotogenously to more distant organs. According to the extent of malignant spread, determined on the basis of surgical and histologic findings, ovarian cancers are classified in four clinical stages. The stage is determined on the basis of surgical findings and histologic examination.
Summary		Vzrokov razvoja raka jajčnikov ne poznamo. Nekatere ženske imajo povečano tveganje za nastanek te nevarne bolezni, ki je najpogostejši vzrok smrti med ginekološkimi raki. Rak se najpogosteje razvija iz celic površinskega epitelija jajčnikov. iz njih lahko nastanejo različne histološke vrste raka. Razlikujemo serozne, mucinozne, endometrioidne, svetlocelične, mešane, nediferencirane in neklasificirane rake ter maligne Brennerjeve tumorje jajčnikov. Z ozirom na stopnjo diferenciacije razlikujemo dobro, zmerno in slabo diferencirane tumorje. Posebna skupina so mejno maligni tumorji, ki imajo svojstvene histološke in biološke lastnosti. Manjši del malignih tumorjev je posledica zasevkov rakov drugih organov. Rak jajčnikov se širi predvsem neposredno po trebušni votlini, prav tako pa limfogeno v retroperitonelni prostor in hematogeno v oddaljene organe. Glede na razširjenost maligh celic razlikujemo štiri stadije raka. Stadij določimo na osnovi kirurškega posega in histopatološke preiskave.
Descriptors		OVARIAN NEOPLASMS NEOPLASM STAGING NEOPLASM INVASIVENESS NEOPLASM SEEDING