Author/Editor     Klocker, J; Sabitzer, H; Raunik, W; Wieser, S; Schumer, J
Title     Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck
Type     članek
Source     Radiol Oncol
Vol. and No.     Letnik 31, št. 2
Publication year     1997
Volume     str. 171-2
Language     eng
Abstract     Forty eight patients with advanced head and neck tumours were treated with irradiation and concomitant chemotherapy with cisplatin, vindesine and hyaluronidase. The disease-free survival rate at 5 years was 47%. The toxic effects were mucositis (48 patients), nausea (25 patients - in 6 patients vomiting), bone marrow depression (15 patients), and peripheral neuropathy (14 patients). The results warrant a randomised trial.
Descriptors     HEAD AND NECK NEOPLASMS
CARCINOMA, SQUAMOUS CELL
CISPLATIN
VINDESINE
HYALURONIDASE
TREATMENT OUTCOME