Author/Editor | Klocker, J; Sabitzer, H; Raunik, W; Wieser, S; Schumer, J | |
Title | Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck | |
Type | članek | |
Source | Radiol Oncol | |
Vol. and No. | Letnik 31, št. 2 | |
Publication year | 1997 | |
Volume | str. 171-2 | |
Language | eng | |
Abstract | Forty eight patients with advanced head and neck tumours were treated with irradiation and concomitant chemotherapy with cisplatin, vindesine and hyaluronidase. The disease-free survival rate at 5 years was 47%. The toxic effects were mucositis (48 patients), nausea (25 patients - in 6 patients vomiting), bone marrow depression (15 patients), and peripheral neuropathy (14 patients). The results warrant a randomised trial. | |
Descriptors | HEAD AND NECK NEOPLASMS CARCINOMA, SQUAMOUS CELL CISPLATIN VINDESINE HYALURONIDASE TREATMENT OUTCOME |