Author/Editor		Friso, Maria L; Loreggian, L; Baiocchi, C; Cesaro, MG; Berti, F; Mazzarotto, R; Fornasiero, A; Calzavara, F
Title		Conservative treatment of anal canal cancer: retrospective study
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 31, št. 2
Publication year		1997
Volume		str. 215-7
Language		eng
Abstract		Between January 1981 and May 1996, thirty partients with anal canal carcinoma were treated with a protocol of radiation therapy alone or in combination with chemotherapy. The patients were divided into 4 stages by International Union against Cancer (UICC) 1987: I stage 8 patients, II stage 16 patients, III stage 5 patients, nobody in stage IV and 1 patient in recurrence. Sixteen patients were treated with external radiation therapy alone, 8 with interstitial 192Ir implant alone, and 6 with the combination of both (dose range 30-70 Gy). Nine patients received concomitant cytotoxic chemotherapy. Toxicities were mild to moderate. Twenty-eight patients were eligible and 2 were lost to follow-up. A complete response (CR) was observed in 19 patients (68%); nobody of these patients had local recurrence and anorectal function was retained. We may conclude that radiotherapy with or withot chemotherapy can provide a good local control and preserve anal function with acceptable morbitidy.
Descriptors		RECTAL NEOPLASMS NEOPLASM STAGING TREATMENT OUTCOME