Author/Editor		Zakotnik, Branko
Title		Maligne bolezni pri bolnikih z aidsom
Translated title		Malignancies in patients with aids
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 36, št. Suppl
Publication year		1997
Volume		str. 157-65
Language		slo
Abstract		Malignant diseases related to AIDS are Kaposi's sarcoma and non-Hodgkin's lymphoma. The incidence of all other malignancies is increased two-fold mainly on the account of: Hodgkin's disease, anal carcinoma, cervical cancer, seminoma, oropharyngeal cancer, melanoma, plasmocytoma and leiomyosarcoma. The treatment of these malignancies does not differ substantially from the treatment in other patients, but the complications of treatment with chemotherapy are increased. The therapeutic nihilism that originally prevailed among clinicians treating AIDS-related malignancies has gradually waned, although many clinical dilemmas remain.
Summary		Maligni bolezni, ki sta nedvomno pogostejši pri bolnikih z aidsom, sta Kaposijev sarkom in Nehodgkinov limfom. Pogosteje se pojavljajo tudi druge maligne bolezni, obolevnost je povečana približno dvakratno predvsem na račun Hodgkinove bolezni, karcinoma anusa, karcinoma vratu maternice, seminoma, karcinoma žrela, melanoma, plazmocitoma in leiomiosarkoma. Zdravljenje teh bolezni se bistveno ne razlikuje od zdravljenja malignih bolezni pri ostalih bolnikih, pač pa so zapleti sistemskega zdravljenja s kemoterapijo bistveno večji. Terapevtski nihilizem, ki je prvotno prevladoval med kliniki, ki so zdravili bolnike z aidsom in maligno boleznijo, je postopoma izzvenel, vendar še vedno ostaja precej kliničnih dilem.
Descriptors		ACQUIRED IMMUNODEFICIENCY SYNDROME SARCOMA, KAPOSI'S LYMPHOMA, NON-HODGKIN'S HIV INFECTIONS