Author/Editor		Dolenc, Leja; Vodušek, David B
Title		Narkolepsija - opis treh bolnikov
Translated title		Narcolepsy - report on three cases
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 66, št. 12
Publication year		1997
Volume		str. 639-43
Language		slo
Abstract		Background. Nercolepsy, a syndrome of excessive sleepiness and abnormalities of rapid eye movement (REM) sleep, is a distinct neurologic disorder with characteristic clinical symptoms and sleep laboratory findings. Symptoms of narcolepsy are: excessive daytime sleepiness, cataplexy, sleep paralysis and hypnogogic/hypnopompic hallucinations. This article describes narcolepsy, as a frequent case of primary hypersomnias, and analyses the characteristics of three narcoleptic patients. Methods and results. Clinical criteria's laboratory examinations, polusomnograpic methods and HLA type are discussed. Three patients who fulfilled clinicaly laboratory and polysomnographic criteria of narcolepsy, and had HLA type significant for this disease are presented. The efficiency of the treatment is discussed. Conclusions. Narcolepsy is a frequent neurological disease, which seems to be diagnosed rarely and late in Slovenia
Summary		Izhodišča. Nerkolepsija, sindrom pretirane zaspanosti in motnje paradoksne faze spanja, je priznana nevrološka bolezen z značilnimi kliničnimi simptomi in posebnimi lastnostmi spanja. Simptomi narkolepsije so: pretirana dnevna zaspanost, katapleksija, paralize v spanju ter hipnagogne/hipnopompne halucinacije. Prispevek obravnava narkolepsijo kot pogost primer primarnih hipersomnij ter analizira značilnosti treh bolnikov z narkolepsijo. Metode in rezultati. Opisani so klinični kriteriji, laboratorijske preiskave, poligrafske metode snemanja spanja ter HLA tipizacija. Prikazani trije bolniki so zadostili kliničnim in poligrafskim kriterijem za narkolepsijo ter imeli zanjo značilno HLA tipizacijo. Opisana je uspešnost zdravljenja narkolepsije. Zaključki. Narkolepsija je pogosta nevfrološka bolezen, za katero se zdi, da je v Sloveniji redko in pozno diagnosticirana.
Descriptors		NARCOLEPSY CATAPLEXY ADULT POLYSOMNOGRAPHY HLA ANTIGENS