Author/Editor		Ho, Anthony K; Sibata, Claudio H; Thomadsen, Bruce R
Title		Comparison of TDF and LQ models using the bioeffects algorithm of a treatment planning system
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 31, št. 3
Publication year		1997
Volume		str. 315-8
Language		eng
Abstract		In this study, two examples, first with two-field AP/PA plans and second with four-field plans are evaluated for Co-60 beams using the bioeffects program of the Radiation Oncology Computer System (ROCS) treatment planning system. The bioeffects algorithm enables the summation of two or more treatment plans. Biomodifier tables, which convert the values of dose per fracrtion delivered over a period of time to Time Dose Fractionation (TDF) are included with the software. The biomedifier table is a standard ROCS twodimensional table. By using the linear-quadratic (LQ) model, the biological equivalent dose versus the physical absorbed dose was determined and input as a new biomodifier table. The distribution of TDF values and the biological equivalent dose using the LQ model shows that the LQ model may be a better choice for a bioeffect algorithm. Furthermore, the LQ model may be implemented in the ROCS system.
Descriptors		NEOPLASMS RADIOTHERAPY, COMPUTER-ASSISTED RADIOTHERAPY PLANNING, COMPUTER-ASSISTED DOSE-RESPONSE RELATIONSHIP, RADIATION