Author/Editor		Strle, Franc; Picken, Roger N; Cheng, Yu; Cimperman, Jože; Maraspin, Vera; Lotrič-Furlan, Stanka; Ružić-Sabljić, Eva; Picken, Maria M
Title		Clinical findings for patients with Lyme borreliosis caused by Borrelia burgdorferi sensu lato with genotypic and phenotypic similarities to strain 25015
Type		članek
Source		Clin Infect Dis
Vol. and No.		Letnik 25, št. 2
Publication year		1997
Volume		str. 273-80
Language		eng
Abstract		In the course of performing culture of Borrelia burgdorferi sensu lato for the diagnosis of Lyme borreliosis in Slovenia, we encountered nine patients who infected with atypical strains. molecular analyses of these strains suggested that they were more closely related to the North American tick isolate, strain 25015 (which to the DN127 genomic group of B. burdorferi sensu lato), than they were to the three species (B. burgdorferi sensu stricto, Borrelia garinii, and Borrelia afzelii) hitherto found to be associated with European Lyme borreliosis. Review of the case histories of these patients revealed some atypical clinical features and variability in clinical presentation. In this study, we present the clinical findings for these patients and discuss their significance for the diagnosis of Lyme borreliosis. The DN127 genomic group shares with B. burgdorferi sensu stricto the distinction of being present in both the Old and New Worlds.
Descriptors		LYME DISEASE BORRELIA BURGDORFERI DNA, BACTERIAL RNA, RIBOSOMAL, 16S EPIDEMIOLOGY, MOLECULAR ANTIBODIES, BACTERIAL ELECTROPHORESIS, GEL, PULSED-FIELD IGG IGM POLYMERASE CHAIN REACTION TICKS NORTH AMERICA SLOVENIA