Author/Editor		Omejc, M; Repše, S; Bračko, M
Title		Is DNA aneuploidy a prognostic factor in gastric cancer?
Type		članek
Source		Acta Chir Hung
Vol. and No.		Letnik 36, št. 1-4
Publication year		1997
Volume		str. 266-9
Language		eng
Abstract		From the results of our study it seems that DNA aneuploidy of gastric cancer has only a limite prognostic value in patients in whom a potentially curative (R0) resection with D2 lymphadenectomy has been performed and whose prognosis is mainly determined by the TNM stage. DNA aneuploidy seems to be the result of tumor progression and becomes an important prognostic factor in stages when the disease is already beyond the reach of current surgical treatment. Flow cytometric determination of DNA content enables observation of changes in cellular DNA during the progression of tumorous growth, but it does not perceive subtle molecular changees which determine the biologic aggressiveness of the tumor.
Descriptors		STOMACH NEOPLASMS DNA, NEOPLASM ANEUPLOIDY CARCINOMA CARCINOMA, SIGNET RING CELL MIDDLE AGE AGE FACTORS SURVIVAL RATE SEX FACTORS NEOPLASM STAGING GASTRECTOMY LYMPH NODE EXCISION LYMPH NODES FLOW CYTOMETRY DIPLOIDY MULTIVARIATE ANALYSIS