Author/Editor     Čarman, Irena
Title     Izolacija in uporaba gliv za razgradnjo oksitetraciklina v micelijski pogači
Translated title     Isolation and utilisation of fungi for degradation of oxytetracycline in a mycelial cake
Type     monografija
Place     Ljubljana
Publisher     Medicinska fakulteta, Biotehniška fakulteta
Publication year     1997
Volume     str. 86
Language     slo
Abstract     Mycelial cake is a waste product of antibiotic oxytetracycline (OTC) production. According to Slovenian legislation it is ranged among special wastes. It contains about 1- 2 % antibiotic that is decomposed within 6 months in composting conditions. From the mycelial cake filamentous fungi were isolated, capable of decomposing the antibiotic and thus accelerating the process of composting. Two species of fungi are moste relevant, namely Trichoderma harzianum and Mucor circinelloides. These two species were submerged cultivated on a rotary shaker under different conditions. The optimal conditions for biomass production of the mentioned isolates and the most efficient decomposition of the antibiotic were determined. The capability of T. harzianum and M. circinelloides to degrade the oxytetracycline in mycelial cakes at laboratory conditions and in the environment at natural conditions was also tested. The composted mycelial cake represents a side product of high quality, mainly suitable for fertilizing feed producing areas. The purpose of the research is to remove the remaining antibiotic by microbiological decompositions and to accelerate in this way the process of composting to obtain a useful and commercial side product of oxytetracycline production.
Descriptors     OXYTETRACYCLINE
BIODEGRADATION
TRICHODERMA
MUCOR
DRUG INDUSTRY
WASTE PRODUCTS
WASTE MANAGEMENT
XENOBIOTICS