| Author/Editor | Skok, Pavel | |
| Title | How efficient is endoscopic injection sclerotherapy in peptic ulcer hemorrhage | |
| Type | članek | |
| Source | Hepatogastroenterology | |
| Vol. and No. | Letnik 44, št. 15 | |
| Publication year | 1997 | |
| Volume | str. 861-5 | |
| Language | eng | |
| Abstract | Backeround/Aims: Peptic ulcer hemorrhage is a common, world-wide problem and a major cause of morbidity and mortality. The aim of this study was to establish the percentage o f patients with bleeding peptic ulcers who were treated surgically because endoscopy failed to stop the hemorrhage. Patients and methods: This retrospective analysis includes patients from our institution who underwent urgent endoscopic examination of the upper digestive tract and hemostatic interuentions with injection therapy (sol. 1:10000 adrenaline and I % polidocanol) between January,1994 and November,1995. Results: Two hundred thirty-three patients with bleeding peptic ulcers were examined:111 with bleeding gastric ulcers (66 males, 45 females; average age 60.21 years, SD +-13.94; span 28 - 94 yrs) and 122 with bleeding duodenal ulcers (95 males, 27 females; auerage age 55.24 years, SD +-17.35; span 16 - 88 yrs). In all patients, injection sclerotherapy was performed. The ulcers were classi*ed according to Forrest*s classification of bleeding activity. In 10 patients (42 %) with acute hemorrhage (6 males; auerage age 532 years, SD +- 5.6; span 53 - 70 yrs: 4 females, auerage age 61.0 years, SD +-11.82; span 51 - 81 yrs), endoscopic hemostasis did not proue success- ful and they were treated operatively. In 5 cases, the cause of hemorrhage was a gastric ulcer and in 5 others, duodenal ulcer. During the postoperatiue period, 5 patients died of complications. Conclusions: Endoscopic hemostasis has been a major therapeutic advancement in the management o f peptic ulcer hemorrhage and has influenced surgical management. Injection sclerotherapy is a low cost, effective and safe procedure which is easy to imple- ment in a uariety of clinical settings. Early electiue operation after initial endoscopic hemostasis is is the wisest choice for elderly patients with coexisting dis- ease and selected patients at high risk for recurrent bleeding. | |
| Descriptors | PEPTIC ULCER HEMORRHAGE SCLEROTHERAPY HEMOSTASIS, ENDOSCOPIC POSTOPERATIVE COMPLICATIONS RETROSPECTIVE STUDIES TREATMENT FAILURE |