Author/Editor		Guček, Andrej; Drinovec, Jože; Kveder, Radoslav; Ponikvar, Rafael; Koželj, Gordana; Simjanovska, Dobrica
Title		Bikarbonatna dializa in cirkulacijska stabilnost 2
Type		monografija
Place		Ljubljana
Publisher		Univerzitetna nefrološka klinika
Publication year		1989
Volume		str. 15
Language		slo
Abstract		8 patients on maintenance hemodialysis (HD) were studied white undergoing acetate (A1) HD 3 times a week, then bicarbonate (B) HD for a week and acetate (A2) HD once more during the third period with use the efficient hemodialyzer. This prospective study was carried out to compare effects of acetate and bicarbonate buffers on cardiovascular stability, tolerance of ultrafiltration and balance of acido-base state. The results indicate that dialysis with bicarbonate (B) leads to significantly smaller increasc of heart rate beats/min than with acetate (A1, A2). There were found less hypotensive episodes (p < 0,05) at B : A1 but difference was not significant at B : A2. There were no statistical differences between blood pressure changes during acetate (A1,A2) and bicarbonate (B) HD. Ultrafiltrations were constant and relatively moderte during each type of HD and there were no statistical significant differences. Plasma bicarbonate concentrations were significant higher at B : A1,A2. Metabolic alkalosis was mild. Oxygenatio of arterial blood was better at B specially 1/2 hour after the beginning of HD (p < 0,005). There were found 2 patients with plasma acetate concentrations higher than 7 mmol/1 and it appers, that this group of patients metabolise acetate more slowly.
Descriptors		HEMODIALYSIS HEMODIALYSIS SOLUTIONS HEART RATE BLOOD PRESSURE ACETATE-COA LIGASE BICARBONATES BLOOD CHEMICAL ANALYSIS HYPOTENSION