Author/Editor		Kaminou, Toshio; Roesch, Josef; Yamada, Ryusaku; Uchida, Barry T; Pavčnik, Dušan; Timmermans, Hans A; Sakaguchi, Shoji; Keller, Frederick S
Title		Percutaneous retroperitoneal splenorenal shunt: an experimental study in swine
Type		članek
Source		Radiology
Vol. and No.		Letnik 206, št. 3
Publication year		1998
Volume		str. 799-802
Language		eng
Abstract		PURPOSE: To evaluate the technical possibility of creating a percutanous retropetoneal splenorenal shunt (PRESS) in swine as a minimally invasive treatment of portal hypertension. MATERIALS AND METHODS: Five normal domestic underwent creation of a PRESS. A modified transjugular intrahepatic portosystemic shunt puncture set was introduced from the right femoral vein into the left renal vein. The proximal splenic vein was punctured transvenously through the retroperitoneal cavity. Noncovered metallic stents were then placed to connect both veins. The animals were sacrificed 1 hour after the procedure, after follow-up splenic venography and necropsy were performed. RESULTS: Puncture of the splenic vein and stent placement were successfully completed in all cases. In four of five cases, the splenic venogram revealed good flow from the splenic vein to the left renal vein through the shunt track 1 hour after creation of the PRESS, and there was no evidence of leakage. No changes in vital signs were noticed. At necropsy, a small retroperitoneal hematoma along the stent and minimal intraperitoneal bleeding were observed. The stents were found in the retroperitoneal cavity connecting both veins in all animals. CONCLUSION: Creation of a PRESS is technically possible, and further experimental studies of its efficacy are warranted.
Descriptors		SPLENORENAL SHUNT, SURGICAL HYPERTENSION, PORTAL RADIOGRAPHY, INTERVENTIONAL RETROPERITONEAL SPACE STENTS SWINE FEASIBILITY STUDIES