Author/Editor		Lotrič-Furlan, Stanka
Title		Humana erlihioza
Translated title		Human ehrlichiosis
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 37, št. Suppl 1
Publication year		1998
Volume		str. 145-53
Language		slo
Abstract		Human granulocytic erhrlichiosis is a tick-borne disease characterised by nonspecific febrile illness with leukopenia and/or thrombocytopenia and evelated activity of liver enzymes. It was first described in 1994 in the Midwest of the united States in an endemic area for Lyme borreliosis, and recently also in Slovenia. Positive polymerase chain reaction result of acute blood or a fourfold convalescent antibody elevation confirms the diagnosis. Clinical features of patients with confirmed acute infection with human granulocytic ehrlichia are very similar to that seen in patients during the first phase of tick-borne encephalitis. Therapy with tetracyclines is highly effective. Infection with human granulocytic ehrlichia must be considered in the differential diagnosis of patients with febrile illnesses after tick bites in Slovenia.
Summary		Humana granulocitna erlihija, ki jo prenašajo klopi vrste Ixodes, povzroča neznačilno vročinsko bolezen z levkopenijo in/ali trombocitopenijo in zvišano aktivnostjo jetrnih encimov. Bolezen je bila prvič dokazana leta 1994 v ZDA v področjih, ki so endemična za lymsko boreliozo, pred kratkim pa tudi v Sloveniji. Diagnozo potrdimo z verižno reakcijo s polimerazo v krvi ali s štirikratnim porastom titra protiteles v parnih vzorcih seruma. Klinična slika akutne okužbe s granulocitno erlihijo, je zelo podobna prvi fazi klopnega meningencefalitisa. Pri zdravljenju so učinkoviti tetraciklini. Avtorica ugotavlja, da je v Sloveniji pri bolniku z vročinsko boleznijo, ki navaja vbod klopa, v diferencialni diagnozi potrebno upoštevati možnosti okužbe v HGE.
Descriptors		EHRLICHIOSIS EHRLICHIA CHAFFEENSIS TICK-BORNE DISEASES