Author/Editor		Kranjec, Igor
Title		Restenoziranje po perkutani transluminalni koronarni angioplastiki
Translated title		Restenosis after percutaneus transluminal coronary angioplasty
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 37, št. Suppl 3
Publication year		1998
Volume		str. 145-52
Language		slo
Abstract		Although the technology of interventional devices has now improved to the point that more complex lesions can be approached with acceptable success rates and safety, recurrence of stenosis remains a major limitation. No matter how advanced and sophisticated a device might be, it achieves its goal only by creating a more or less controlled, yet always substantial injury to the vessel wall. The resulting healing process is directly related to the degree of the inflicted injury. This paper reviews the available clinical information about factors that affect restenosis rates, assesses the critical methodological issues of restenosis, and makes recommendations for current management. Some of the newer pharmacological trials for the prevention of restenosis are briefly described.
Summary		Perkutane koronarne revaskularizacijske metode so se v zadnjem času izpopolnile do te mere, da se lahko varno lotevamo kompleksnejših lezij. Kljub temu razvoju ostaja restenoziranje poglavitna hiba v dolgoročni uspešnosti metode. Katerakoli izmed tovrstnih revaskularizacijskih naprav ustvari večjo koronarno svetlino le na račun kontrolirane poškodbe žilne stene. Celjenje žilne rane je navadno sorazmerno stopnji povzročene poškodbe. V članku so povzeti klinični podatki, ki vplivajo na pogostnost restenoziranja in omenjene težave v zvezi z bolezenskim prepoznavanjem. Navedeni so tudi sodobni principi perkutanega in farmakološkega razreševanja koronarnih restenoz.
Descriptors		ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY CORONARY VESSELS CORONARY DISEASE